Proinflammatory mediators and osteoarthritis
نویسندگان
چکیده
منابع مشابه
Soluble Mediators in Posttraumatic Wrist and Primary Knee Osteoarthritis
Background: New discoveries about the pathophysiology changed the concept that all forms of osteoarthritis are alike; this lead to the delineation of different phenotypes such as age, trauma or obese related forms. We aim to compare soluble mediator profiles in primary knee and posttraumatic wrist osteoarthritis. Based on the general faster progression rate of wrist osteoarthritis, we hypothes...
متن کاملsoluble mediators in posttraumatic wrist and primary knee osteoarthritis
background: new discoveries about the pathophysiology changed the concept that all forms of osteoarthritis are alike; this lead to the delineation of different phenotypes such as age, trauma or obese related forms. we aim to compare soluble mediator profiles in primary knee and posttraumatic wrist osteoarthritis. based on the general faster progression rate of wrist osteoarthritis, we hypothes...
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BACKGROUND Vascular endothelial growth factor (VEGF; vascular permeability factor) is one of the most potent proangiogenic cytokines, and it plays a central role in mediating the process of angiogenesis or new blood vessel formation. Neutrophils (PMNs) recently have been shown to produce VEGF. HYPOTHESIS The acute inflammatory response is a potent stimulus for PMN-directed angiogenesis. MET...
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The diabetes-atherosclerosis relationship remains to be fully defined. Repeated prolonged hyperglycemia, increased ROS production and endothelial dysfunction are important factors. One theory is that increased blood levels of heat shock protein (HSP)60 are proinflammatory, through activation of innate immunity, and contribute to the progression of vascular disease. It was hypothesized that impr...
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ژورنال
عنوان ژورنال: Osteoarthritis and Cartilage
سال: 1999
ISSN: 1063-4584
DOI: 10.1053/joca.1998.0177